Research area

Epilepsy & Seizures

Most epilepsy research is about the seizures that carry on despite treatment, and about living more safely while they do.

About the area

What research here looks at

Epilepsy is a tendency to have seizures that start in the brain. Many people find a medicine that controls them, and research in this area mostly concerns those who have not, or who live with side effects they would rather not have.

Studies test new medicines added to the ones a person already takes, nerve stimulation devices, dietary approaches and wearables that detect a seizure and call for help. Others follow how seizures change over years.

A man in a white shirt reading his phone in a bright kitchen
Kinds of study

The studies you are likely to find

Add-on medicine studies

Test a new medicine taken alongside current ones, compared with placebo or with standard care.

Device studies

Look at implanted or external stimulators and how well they reduce seizures.

Detection studies

Try out watches and sensors that notice a seizure and alert someone.

Diet studies

Follow structured eating plans, usually with a dietitian guiding every step.

Taking part

What taking part
can involve

Every study is different, and its consent form sets out exactly what it asks. These are the things studies in this area often include.

  • A seizure diary kept for a set baseline period before anything changes
  • EEG recordings, sometimes overnight or at home
  • Blood tests to check medicine levels
  • Regular clinic visits and phone check-ins
  • Questions about sleep, mood and side effects
In the listings

Lines that listings in this area
often publish

A confirmed diagnosis, with the seizure type named by a specialist

Usually needed

Seen in many listings

Seizures still happening while on at least one medicine

Usually needed

Seen in many listings

How many anti-seizure medicines you take now, and whether doses have been steady

Worth asking about

Seen in many listings

A diary of seizures over the weeks before the study begins

Worth asking about

Seen in many listings

A recent episode of prolonged seizures needing emergency care

A common reason for a no

Seen in many listings

Whether someone at home can help record seizures you may not remember

Worth asking about

Seen in many listings

These are patterns, not rules. Each study writes its own criteria, and only its team can say how a line applies to you.

Before you join

Questions worth asking the study team

  1. Do I keep taking all of my current medicines?
  2. How should I record seizures, and does someone else need to help?
  3. What happens if my seizures get worse during the study?
  4. Does the study affect what I am allowed to do, such as driving?

Look for epilepsy and seizures studies

The register opens in a new tab, already set to this condition and to studies that are recruiting.

Search ClinicalTrials.gov

Orva does not run or choose these studies. Contact the team a listing names.

Guides

Guides that work for any area